The ProPic™II integrates imaging and picking on a single platform. Many low abundance proteins can be detected using its high-resolution image acquisition system with Peltier-cooled camera (CCD) with 16-bit line scanning, UV-B light source, large imaging/picking area, full and light-tight enclosure, direct imaging of gels stained with all commonly used visible and fluorescent stains, easy-to-use software for image acquisition (and picking) and seamless integration with DIGE. For users who require extended gel analysis prior to picking, any image analysis software package can be used to create a pick list that can then be downloaded to the Investigator ProPic™II for protein excision.