High-Performance Time-Resolved Fluorescence Microplate Reader

The RUBYstar enables highly sensitive time-resolved fluorescence detection by applying europium chelate or cryptate fluorophores. These compounds are excited with the high-energy laser and show long fluorescence lifetimes (several hundred microseconds), large Stoke's shifts and intensive fluorescence peak profiles at 620 nm. Therefore with the RUBYstar, backgrounds are reduced and the signal-to-noise ratio is increased, so giving maximum sensitivity.

• The fastest and most sensitive HTRF® in the world
• High energy laser light source (337 nm)
• Single photon counting detection system
• Sensitive measurements for reading low reagent concentrations
• Low volume reading in 384-well format
• Faster reading times (<3 min for 384-well format)
• Standard mode programming for HTS-readings
• Advanced mode programming for highest flexibilities (e.g. with decay curve monitoring)
• Simultaneous dual emission measurements at 620 nm and 665 nm
• Real time quenching correction by ratio calculation (US patent 5,527,684)

For BMG LABTECH application notes that can be performed on the RUBYstar, please click here.

The RUBYstar reader can be used for both assay development and high throughput screening for a wide range of applications e.g. biomolecular interactions, receptor binding assays and molecular biological applications.

For more information about HTRF®and the TR-FRET technology, please see this website: www.htrf.com

HTRF is a registered trademark belonging to Cisbio International