Nexterion® Slide AL is ideally suited for covalent immobilization of aminomodified nucleic acids or small protein fragments such as peptides. The aldehyde- group will reversibly react with the accessible primary amino-groups of the biomolecules to form a Schiff’s Base. Following the reduction with sodium borohydride there is an irreversible immobilization of the probes and deactivation of any remaining un-reacted aldehyde-groups. The density of aldehyde-groups on the surface remains constant over the entire surface of the slide and is adjusted to provide optimal binding capacity.

Technical Instructions for Spotting Microarrays (short version) PDF

Technical Instructions for Spotting Microarrays PDF

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