Home > Custom peptide synthesis

Custom peptide synthesis

Synthetic peptides are widely used, e.g. as models to study various aspects of protein structure and function and antibody production. Synthetic peptides are chemically well-defined enities that can be varied in sequence and length.

  • C-terminal group can be chosen as amide group or as carboxyl group
  • Fully amino acid side chain protection
  • Partial amino acid side chain protection of the peptide
  • Incorporation of D-amino acids or amino acid derivatives
  • KLH, BSA and OVA coupling to the carrier proteins
  • Phosphorylated and biotinylated peptides
  • Multi Analog Production

Peptide synthesis scales

Service Features Field of application
Custom peptide synthesis Standard scale (from 2 mg up to 50-100mg) R&D - early leads
Medium scale (from hundreds of mgs up to grams) R&D - early development
Mini-bulk (from tens of grams up to hundred grams) Clinical trials (early phase)
Custom peptide arrays Crude, small scale, high numbers, low cost, fast response R&D - Discovery
Custom peptide libraries Purified, small scale, high numbers, low cost, fast response R&D - Discovery

 

All synthetic activities performed are under GLP (Good Laboratory Practice), mini-bulk is now also available under strict cGMP.
Other peptide products and services include:

  • Fluorescent labelled peptides
  • Glycosylated peptides
  • Modified peptides
  • Bioactive peptides
  • Amino acid derivatives and Reagents for peptide synthesis
  • Custom polyclonal antibodies
  • Custom recombinant antibodies
  • Analysis of peptides and proteins

Our peptides are generally delivered as a lyophilized (fluffy), dry material. The final yield of your peptide will depend on the sequence, the length and the purity required. As a guideline we offer 3 standard peptide categories:

Peptide categories

purity yield
50 - 70% 5, 25, 50 or 100 mg
> 80% 2, 10 or 50 mg
>95% 2, 5 or 10 mg

 

Isogen Life Science is a leading manufacturer of high quality custom peptides, and successfully synthesizes thousands of peptides for years for the scientific community and has reached the highest standards of quality, service, and technical expertise.
We offer peptides in different amounts and different purity grade according customer needs. Whatever the scale of synthesis chosen, the customers are guaranteed of receiving high quality peptides: the chemical structure of each peptide is determined by MALDI-TOF mass spectrometry analysis and the purity is certificated by HPLC chromatograms.
Very fast delivery is guaranteed all over the word by rapid production and by express carrier shipping of the vials containing the lyophilized product.

We maintain absolute confidentiality. If required, we will be pleased to sign a secrecy agreement before receiving your peptide structure.

In addition to the standard peptide synthesis service, Isogen Life Science provides peptide arrays and peptide libraries, as well as several peptide modifications and conjugations for a variety of applications:

  • Phospho Peptides: Phospho Serine, Threonine, and Tyrosine
  • Glycopeptides
  • MAP peptides
  • Cyclic Peptides: Disulfide and head to tail
  • Special Modifications including: Fluoroscein, Rhodamine, Cy3, AMC, Biotin, d-amino acids, stable isotopes, EDANS, Dabcyl, Dansyl, Abz, thiolactic acids, and many others

Please visit the other web-site sections: custom peptide libraries, peptide arrays, fluorescent labeled peptides, modified peptides, bioactive peptides, bulk and cGMP peptides.

Please contact us to discuss other additional services: design of peptides with desired functions and requirements, cyclic and/or branched peptides, change in the counterion, etc.